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Cervical Health Awareness Month

Cervical insufficiency (CI), also known as incompetent cervix, is an obstetric complication in which the cervix is unable to support a full-term pregnancy. This condition is characterised by a history of recurrent pregnancy losses in the second or early-third trimester with no other cause. The prevalence of cervical insufficiency has been estimated to affect 0.5% of the general obstetric population and 8% of patients with a history of previous midtrimester miscarriages (approximately 16-24 weeks gestational age).1

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2024-02-01 to 2024-02-29

Pathophysiology of CI

The pathophysiology of CI is not well understood, although all causes are related to compromise in the structure or function of the cervix. Congenital causes of CI include Mullerian anomalies, collagen and elastin deficiencies (e.g., Ehlers-Danlos or Marfan syndrome), other uterine malformations, and diethylstilbestrol (DES) exposure.1 Acquired causes include cervical trauma sustained during a previous delivery, loop electrosurgical excision procedure (LEEP), cervical conization, and mechanical dilation during uterine evacuation procedure.
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Polycystic Ovarian Syndrome (PCOS)

Another risk factor for CI is polycystic ovarian syndrome (PCOS). The mechanism of hyperandrogenism and its effect on cervical ripening is not fully understood. However, patients with PCOS and associated insulin resistance are at an increased risk for negative pregnancy outcomes including development of CI early in pregnancy and termination of pregnancy at an earlier gestational age.3 Individuals with PCOS may need increased cervical monitoring in the second.

History and Physical Examination

Patients with CI typically present with a history of 1 or more pregnancy losses characterized by early cervical dilation without uterine contractions, pain, or other labour signs. A connective tissue disorder or history of cervical trauma supports the diagnosis. Symptoms of CI are abdominal pressure or cramping, backache, pelvic pressure, increased volume of vaginal discharge (mucous, watery, light bloody discharge), or bleeding.

Diagnosis of Cervical Insufficiency

Patients with CI typically present with a history of 1 or more pregnancy losses characterized by early cervical dilation without uterine contractions, pain, or other labour signs. A connective tissue disorder or history of cervical trauma supports the diagnosis. Symptoms of CI are abdominal pressure or cramping, backache, pelvic pressure, increased volume of vaginal discharge (mucous, watery, light bloody discharge), or bleeding.

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